Lose Weight With Metformin

Metformin, also known by its brand names Glucophage, Riomet, and Fortamet, is an oral medication primarily used to treat type 2 diabetes.

In addition to its glucose-lowering effects, Metformin has shown promise in helping with weight loss in individuals with type 2 diabetes or prediabetes.

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What is Metformin ?

Metformin belongs to a class of medications called biguanides. It works by reducing the amount of glucose (sugar) produced by the liver and increasing insulin sensitivity in the body. This helps to lower blood sugar levels and regulate glucose metabolism.

Metformin is available under various brand names, including Glumetza, Riomet, and Fortamet. It comes in both immediate-release and extended-release tablet forms.

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How does Metformin work?

Metformin primarily works by inhibiting the production of glucose in the liver and enhancing the body's sensitivity to insulin. It helps your body utilize glucose more efficiently, thus preventing excessive glucose buildup in the bloodstream. By reducing blood sugar levels and optimizing insulin function, Metformin can indirectly contribute to weight loss.

Is Metformin safe and effective for weight loss?

Metformin has shown promise in aiding weight loss, especially in individuals with obesity who have Type II Diabetes Mellitus. A meta-analysis of several studies on metformin use in overweight or obese individuals with diabetes found that the medication was associated with a modest but statistically significant weight loss compared to placebo. The average weight loss observed in these studies ranged from 1.1 kg to 3.6 kg over a duration of 3 to 12 months.

It is important to note that individual results may vary, and metformin should not be relied upon as a standalone weight-loss solution. Weight loss with metformin is typically mild to moderate, and it works best when combined with a healthy diet, regular exercise, and lifestyle modifications. Metformin should be used as part of an overall weight loss plan prescribed and supervised by a doctor.

How much does Metformin cost?

The cost for a one-month supply of metformin can range from $10 to $240, depending on these factors.

How is Metformin taken?

Metformin is typically taken orally, usually with meals to reduce gastrointestinal side effects. The dosage and frequency of Metformin will be determined by your healthcare professional based on various factors, including your blood sugar levels, response to the medication, and any other existing medical conditions.

It is essential to follow the prescribed instructions provided by your healthcare professional and not adjust the dosage without medical guidance.

Understanding your Metformin dosage

Metformin is available in various dosage strengths, typically ranging from 500mg to 1000mg tablets. Your healthcare professional will determine the appropriate starting dose and may gradually increase it if necessary. The aim is to find the minimum effective dose while minimizing side effects.

Dosage may also be adjusted based on individual factors such as renal function (kidney health). It's crucial to communicate any changes in your health status or medication regimen to your doctor for proper monitoring and dosage adjustments if needed.


Side Effects of Metformin

While Metformin is generally well-tolerated, some individuals may experience side effects. These can include gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort. These side effects are usually temporary and diminish as the body adjusts to the medication. It's important to discuss any persistent or severe side effects with your healthcare professional.

Additionally, although rare, Metformin can cause a serious but very uncommon side effect called lactic acidosis. This is more likely to occur in individuals with impaired kidney function or those taking higher doses of the medication. It's crucial to inform your doctor immediately if you experience symptoms such as weakness, fatigue, muscle pain, trouble breathing, or a slow or irregular heartbeat.

Alternative medication

Semaglutide is one of the multiple GLP-1 weight-loss classes of drugs. Other GLP-1 drug classes include: