Click continue to see content specific to your region or location.

Lose Weight With Zepbound

Zepbound™ is an injectable prescription medicine used for weight loss in adults with obesity or overweight and who also have weight-related medical problems.

It contains the active ingredient tirzepatide and works by activating both GIP and GLP-1 receptors to reduce appetite, lower blood sugar levels, and promote weight loss. It is used along with a reduced-calorie diet and increased physical activity.

What is Zepbound?

Zepbound contains the active ingredient tirzepatide, which is a novel dual GIP and GLP-1 receptor agonist. GIP and GLP-1 are naturally occurring hormones in the body that play a role in regulating blood sugar levels, insulin secretion, and feelings of hunger and fullness.

By activating both GIP and GLP-1 receptors, tirzepatide helps to stimulate insulin secretion, reduce glucagon secretion (which lowers blood sugar levels), slow down the movement of food from the stomach into the small intestine, and increase satiety. These actions contribute to reduced appetite, decreased caloric intake, and weight loss.

How does the Zepbound work?

Zepbound's dual action on GIP and GLP-1 receptors leads to several beneficial effects for weight management. By stimulating GLP-1 receptors, tirzepatide helps lower blood sugar levels, decrease appetite, and slow down stomach emptying, which results in greater satiety and reduced food intake.

On the other hand, activation of GIP receptors helps to enhance insulin secretion in response to meals, further aiding in blood sugar control and promoting weight loss. Together, these effects help patients achieve and maintain weight loss goals.

Is Zepbound safe and effective for weight loss?

In clinical trials, patients using Zepbound 5mg once weekly experienced significant weight loss. Over 72 weeks, patients in this dose group lost an average of 16.1 kg (35.5 lb) when used in combination with diet and exercise. Patients on higher doses of 10mg and 15mg once weekly experienced even greater weight loss. However, it is important to note that individual results may vary.

Zepbound has been generally well-tolerated in clinical trials, but like all medications, it can have side effects. The overall safety and effectiveness of Zepbound for weight loss have been established in clinical studies, and your doctor will help you understand if the medication is suitable for your specific circumstances.

How much does Zepbound cost?

The cost of Zepbound may vary depending on factors such as insurance coverage and the specific pharmacy used. The out-of-pocket cost for Zepbound is approximately $1,059.87 for a pre-filled single-dose pen.

However, it is worth noting that there may be savings card programs, patient assistance programs, or other discounts available that can help reduce the cost of the medication. It is advisable to check with your insurance provider, the official Zepbound website, or consult a pharmacist for more information on potential cost-saving options.

How is the Zepbound taken?

Zepbound is self-administered as a once-weekly injection under the skin (subcutaneous injection) using a pre-filled single-dose pen. The injection can be given into the abdomen, thigh, or upper arm. It is recommended to rotate injection sites to minimize the risk of injection site reactions.

The medication can be taken at any time of day, preferably around the same time each week, and does not necessarily have to be associated with meals. Before starting Zepbound, your doctor will provide specific instructions on how to properly administer the injections, including techniques for safe injection practices.

Understanding your Zepbound dosage

The starting dose of Zepbound is 2.5mg injected subcutaneously once a week. Your healthcare provider may increase the dose to 10mg and then potentially up to 15mg based on your response and tolerability.

The dose adjustment will depend on factors such as your weight loss progress, glycemic control, and the presence of side effects. It is important to follow the prescribed dosage and administration instructions provided by your doctor.

If you miss a dose, you can take it within 4 days of the missed dose. If more than 4 days have passed, skip the missed dose and continue with your regular dosing schedule. Do not take extra doses to make up for a missed dose.

Warnings

Side Effects of Zepbound

Common side effects of Zepbound may include abdominal pain, constipation, diarrhea, fatigue, injection site reactions (such as redness, swelling, or itching at the injection site), nausea, and vomiting.

These side effects are generally mild to moderate and often resolve on their own over time. However, if they persist or worsen, it is important to consult with your healthcare provider. Serious side effects may include signs of an allergic reaction (such as rash, itching, or difficulty breathing) or pancreatitis (severe abdominal pain that lasts several days, nausea, and vomiting).

In rare cases, Zepbound has been associated with the development of thyroid tumors. If you experience severe stomach problems, eye side effects, signs of a thyroid tumor, gallbladder problems, low blood sugar symptoms, or kidney problems, it is important to contact your doctor immediately.